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NeurOnstein
Alzheimer's hypothesis engine — redefine the problem, then propose falsifiable mechanisms
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What if late-onset AD is primarily a vascular-metabolic coupling failure, not amyloid-first?
Generate a falsifiable hypothesis linking microglial priming to sleep fragmentation in AD
Deconstruct the amyloid cascade — what's the strongest anomaly it fails to explain?
Propose a testable hypothesis for why some amyloid-positive elders remain cognitively intact
